I think that user donations are easier when an instance has a good focus. There are some other instances I can think of where the donation model has been enough to cover things. In addition to feddit.dk and beehaw, an instance I use most of the time, ani.social, is more than covered by donations last I checked. It looks like @hitagi@ani.social even took away the donate link in the sidebar. Never mind, I am just blind. I didn’t notice the little Ko-fi badge at the bottom. I was looking for a text link.
I work in pharma, regularly writing and filing things with the FDA (and other agencies), and this has been a topic of conversation at work. The good news for people is that the EMA is still a thing in the EU. So, at least the large pharma companies (like the one I work for), are likely to not really change much about their quality control/processes/etc. because we will still need to conform to the EMA guidelines which are typically in line with the current FDA (sometimes more strict, sometimes less so). The real quality concern would be smaller companies that only file for products in the US. They would only need to meet whatever new FDA guidelines come into effect (if they even do, changing stuff like GMP guidance is extremely complicated and time consuming) since the US is their only market.